Structure-based design of ketone-containing, tripeptidyl human rhinovirus 3C protease inhibitors.
Dragovich, P S
Structure-based design of ketone-containing, tripeptidyl human rhinovirus 3C protease inhibitors. [electronic resource] - Bioorganic & medicinal chemistry letters Jan 2000 - 45-8 p. digital
Publication Type: Comparative Study; Journal Article
0960-894X
10.1016/s0960-894x(99)00587-9 doi
3C Viral Proteases
Antiviral Agents--chemical synthesis
Cells, Cultured
Cysteine Endopeptidases--metabolism
Cysteine Proteinase Inhibitors--chemical synthesis
Drug Design
Humans
Inhibitory Concentration 50
Ketones--chemical synthesis
Kinetics
Oligopeptides--chemical synthesis
Rhinovirus--drug effects
Structure-Activity Relationship
Viral Proteins
Structure-based design of ketone-containing, tripeptidyl human rhinovirus 3C protease inhibitors. [electronic resource] - Bioorganic & medicinal chemistry letters Jan 2000 - 45-8 p. digital
Publication Type: Comparative Study; Journal Article
0960-894X
10.1016/s0960-894x(99)00587-9 doi
3C Viral Proteases
Antiviral Agents--chemical synthesis
Cells, Cultured
Cysteine Endopeptidases--metabolism
Cysteine Proteinase Inhibitors--chemical synthesis
Drug Design
Humans
Inhibitory Concentration 50
Ketones--chemical synthesis
Kinetics
Oligopeptides--chemical synthesis
Rhinovirus--drug effects
Structure-Activity Relationship
Viral Proteins