3-Aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-ones: tricyclic heteroaromatic derivatives as a new class of benzodiazepine receptor ligands.

Primofiore, G

3-Aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-ones: tricyclic heteroaromatic derivatives as a new class of benzodiazepine receptor ligands. [electronic resource] - Journal of medicinal chemistry Jan 2000 - 96-102 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0022-2623

10.1021/jm991131h doi


Animals
Anticonvulsants--chemical synthesis
Benzimidazoles--chemical synthesis
Brain--metabolism
Cattle
Convulsants--chemical synthesis
Diazepam--antagonists & inhibitors
Flumazenil--pharmacology
GABA Modulators--pharmacology
In Vitro Techniques
Ligands
Membranes--drug effects
Mice
Models, Molecular
Radioligand Assay
Receptors, GABA-A--drug effects