MS-8209, an amphotericin B analogue, delays the appearance of spongiosis, astrogliosis and PrPres accumulation in the brain of scrapie-infected hamsters.

Adjou, K T

MS-8209, an amphotericin B analogue, delays the appearance of spongiosis, astrogliosis and PrPres accumulation in the brain of scrapie-infected hamsters. [electronic resource] - Journal of comparative pathology Jan 2000 - 3-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9975

10.1053/jcpa.1999.0338 doi


Amphotericin B--analogs & derivatives
Animals
Anti-Bacterial Agents--therapeutic use
Antiviral Agents--therapeutic use
Astrocytes--drug effects
Blotting, Western
Brain--drug effects
Cricetinae
Disease Models, Animal
Edema--drug therapy
Female
Glial Fibrillary Acidic Protein--metabolism
Gliosis--drug therapy
Immunohistochemistry
Mesocricetus
Prions--metabolism
Scrapie--drug therapy