Malignant transformation of neurofibromas in neurofibromatosis 1 is associated with CDKN2A/p16 inactivation.

Nielsen, G P

Malignant transformation of neurofibromas in neurofibromatosis 1 is associated with CDKN2A/p16 inactivation. [electronic resource] - The American journal of pathology Dec 1999 - 1879-84 p. digital

Publication Type: Journal Article

0002-9440

10.1016/S0002-9440(10)65507-1 doi


Adolescent
Adult
Aged
Cell Transformation, Neoplastic--genetics
Child
Cyclin-Dependent Kinase Inhibitor p16--metabolism
DNA Methylation
Female
Gene Deletion
Genes, p16
Humans
Immunohistochemistry
Male
Middle Aged
Neurofibroma--genetics
Neurofibromatosis 1--genetics
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational