Cell surface presenilin-1 participates in the gamma-secretase-like proteolysis of Notch.

Ray, W J

Cell surface presenilin-1 participates in the gamma-secretase-like proteolysis of Notch. [electronic resource] - The Journal of biological chemistry Dec 1999 - 36801-7 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.274.51.36801 doi


3T3 Cells
Amyloid Precursor Protein Secretases
Animals
Aspartic Acid Endopeptidases
Endopeptidases--genetics
Humans
Membrane Proteins--genetics
Mice
Mutation
Presenilin-1
Receptors, Cell Surface--metabolism
Receptors, Notch
Signal Transduction