The contribution of P-glycoprotein to pharmacokinetic drug-drug interactions.

Yu, D K

The contribution of P-glycoprotein to pharmacokinetic drug-drug interactions. [electronic resource] - Journal of clinical pharmacology Dec 1999 - 1203-11 p. digital

Publication Type: Journal Article; Review

0091-2700

10.1177/00912709922012006 doi


ATP Binding Cassette Transporter, Subfamily B, Member 1--metabolism
Antineoplastic Agents--pharmacokinetics
Aryl Hydrocarbon Hydroxylases
Biological Transport--drug effects
Cytochrome P-450 CYP3A
Cytochrome P-450 Enzyme System--metabolism
Drug Interactions
Drug Resistance, Multiple--physiology
Humans
Models, Biological
Oxidoreductases, N-Demethylating--metabolism
Pharmacokinetics
Substrate Specificity