How an inhibitor of the HIV-I protease modulates proteasome activity.

Schmidtke, G

How an inhibitor of the HIV-I protease modulates proteasome activity. [electronic resource] - The Journal of biological chemistry Dec 1999 - 35734-40 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.274.50.35734 doi


Animals
Binding Sites
Canavanine--pharmacology
Cell Line
Cysteine Endopeptidases--chemistry
Cytomegalovirus
HIV Protease Inhibitors--chemistry
HIV-1--enzymology
Humans
Immediate-Early Proteins--metabolism
Iodine Radioisotopes
Kinetics
Mice
Models, Molecular
Multienzyme Complexes--chemistry
Oligopeptides--pharmacokinetics
Proteasome Endopeptidase Complex
Protein Conformation
Protein Structure, Quaternary
Ritonavir--chemistry
Saccharomyces cerevisiae--enzymology
Sulfones--pharmacokinetics
Ubiquitins--metabolism