Role of inflammatory infiltrate in activation and effector function of cloned islet reactive nonobese diabetic CD8+ T cells: involvement of a nitric oxide-dependent pathway.

Gurlo, T

Role of inflammatory infiltrate in activation and effector function of cloned islet reactive nonobese diabetic CD8+ T cells: involvement of a nitric oxide-dependent pathway. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Dec 1999 - 5770-80 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0022-1767


Animals
CD8-Positive T-Lymphocytes--immunology
Cell Movement
Clone Cells
Diabetes Mellitus, Type 1--immunology
Female
H-2 Antigens
Histocompatibility Antigen H-2D
Histocompatibility Antigens Class II--immunology
Interferon-gamma--metabolism
Islets of Langerhans--cytology
Leukocytes, Mononuclear--immunology
Lymphocyte Activation
Lysine--analogs & derivatives
Macrophages--immunology
Major Histocompatibility Complex
Mice
Mice, Inbred NOD
Nitric Oxide--metabolism
Nitric Oxide Synthase--antagonists & inhibitors
Nitric Oxide Synthase Type II
Signal Transduction
Spleen--cytology