Role of the cyclic AMP-protein kinase A pathway in lipopolysaccharide-induced nitric oxide synthase expression in RAW 264.7 macrophages. Involvement of cyclooxygenase-2.

Chen, C C

Role of the cyclic AMP-protein kinase A pathway in lipopolysaccharide-induced nitric oxide synthase expression in RAW 264.7 macrophages. Involvement of cyclooxygenase-2. [electronic resource] - The Journal of biological chemistry Oct 1999 - 31559-64 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.274.44.31559 doi


Animals
Bucladesine--pharmacology
Cell Compartmentation
Cell Line
Cholera Toxin--pharmacology
Colforsin--pharmacology
Cyclic AMP-Dependent Protein Kinase Type II
Cyclic AMP-Dependent Protein Kinases--antagonists & inhibitors
Cyclooxygenase 2
Cyclooxygenase 2 Inhibitors
Cyclooxygenase Inhibitors--pharmacology
Cytoplasm--enzymology
Isoenzymes--metabolism
Isoquinolines--pharmacology
Lipopolysaccharides--immunology
Macrophages--enzymology
Mice
Models, Biological
NF-kappa B--metabolism
Nitric Oxide Synthase--biosynthesis
Nitric Oxide Synthase Type II
Nitrites--metabolism
Prostaglandin-Endoperoxide Synthases--metabolism
Signal Transduction