Loss of responsiveness to transforming growth factor beta induces malignant transformation of nontumorigenic rat prostate epithelial cells.

Tang, B

Loss of responsiveness to transforming growth factor beta induces malignant transformation of nontumorigenic rat prostate epithelial cells. [electronic resource] - Cancer research Oct 1999 - 4834-42 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0008-5472


Animals
Apoptosis--drug effects
Cell Differentiation--drug effects
Cell Division--drug effects
Cell Line
Cell Transformation, Neoplastic
Epithelial Cells
Extracellular Matrix Proteins--genetics
Gene Expression Regulation--drug effects
Humans
Male
Mice
Mice, Nude
Prostate
Prostatic Neoplasms--genetics
Protein Serine-Threonine Kinases
Rats
Receptor, Transforming Growth Factor-beta Type II
Receptors, Transforming Growth Factor beta--genetics
Recombinant Proteins--metabolism
Transfection
Transforming Growth Factor beta--pharmacology
Transplantation, Heterologous