Further studies on oxygenated tryptamines with LSD-like activity incorporating a chiral pyrrolidine moiety into the side chain.

Gerasimov, M

Further studies on oxygenated tryptamines with LSD-like activity incorporating a chiral pyrrolidine moiety into the side chain. [electronic resource] - Journal of medicinal chemistry Oct 1999 - 4257-63 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0022-2623

10.1021/jm990325u doi


Animals
Binding, Competitive
Discrimination Learning--drug effects
Frontal Lobe--metabolism
In Vitro Techniques
Indoles--chemical synthesis
Lysergic Acid Diethylamide--pharmacology
Male
Pyrrolidines--chemical synthesis
Radioligand Assay
Rats
Rats, Sprague-Dawley
Receptor, Serotonin, 5-HT2A
Receptors, Serotonin--metabolism
Stereoisomerism
Structure-Activity Relationship
Tryptamines--chemical synthesis