Cyclosporin A and tacrolimus (FK506) suppress expression of inducible nitric oxide synthase in vitro by different mechanisms.

Dusting, G J

Cyclosporin A and tacrolimus (FK506) suppress expression of inducible nitric oxide synthase in vitro by different mechanisms. [electronic resource] - British journal of pharmacology Sep 1999 - 337-44 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0007-1188

10.1038/sj.bjp.0702782 doi


Animals
Blotting, Southern
Cell Line
Cyclosporine--pharmacology
Depression, Chemical
Enzyme Inhibitors--pharmacology
Immunosuppressive Agents--pharmacology
Interferon-gamma--pharmacology
Lipopolysaccharides--pharmacology
Macrophages--drug effects
Male
Mice
Muscle, Smooth, Vascular--drug effects
Nitric Oxide Synthase--antagonists & inhibitors
Nitric Oxide Synthase Type II
Nitrites--metabolism
RNA, Messenger--biosynthesis
Rats
Rats, Sprague-Dawley
Recombinant Proteins
Reverse Transcriptase Polymerase Chain Reaction
Tacrolimus--pharmacology