Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense.

Wilson, C L

Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense. [electronic resource] - Science (New York, N.Y.) Oct 1999 - 113-7 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0036-8075

10.1126/science.286.5437.113 doi


Amino Acid Sequence
Animals
Catalysis
Cytoplasmic Granules--enzymology
Escherichia coli--growth & development
Escherichia coli Infections--immunology
Female
Humans
Immunity, Innate
Immunity, Mucosal
Intestinal Mucosa--enzymology
Intestine, Small--enzymology
Male
Matrix Metalloproteinase 7
Metalloendopeptidases--genetics
Mice
Molecular Sequence Data
Paneth Cells--enzymology
Protein Precursors--genetics
Recombinant Fusion Proteins--metabolism
Salmonella typhimurium--growth & development
Tissue Extracts--pharmacology