Targeted disruption of the beta adducin gene (Add2) causes red blood cell spherocytosis in mice.

Gilligan, D M

Targeted disruption of the beta adducin gene (Add2) causes red blood cell spherocytosis in mice. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Sep 1999 - 10717-22 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0027-8424

10.1073/pnas.96.19.10717 doi


Anemia--genetics
Animals
Blotting, Northern
Calmodulin-Binding Proteins--genetics
Erythrocytes--cytology
Erythroid Precursor Cells--metabolism
Exons
Mice
Mice, Inbred C57BL
Mice, Knockout
Models, Genetic
Mutagenesis
Osmolar Concentration
Osmotic Fragility--genetics
Poly A--analysis
RNA--analysis
Spherocytosis, Hereditary--genetics
Spleen--metabolism
Tissue Distribution