N-substituted adenosines as novel neuroprotective A(1) agonists with diminished hypotensive effects.

Knutsen, L J

N-substituted adenosines as novel neuroprotective A(1) agonists with diminished hypotensive effects. [electronic resource] - Journal of medicinal chemistry Sep 1999 - 3463-77 p. digital

Publication Type: Journal Article

0022-2623

10.1021/jm960682u doi


Adenosine--analogs & derivatives
Animals
Blood Pressure--drug effects
Brain--drug effects
Brain Ischemia--drug therapy
Cardiovascular System--drug effects
Cell Line
Gerbillinae
Guinea Pigs
Hypotension--metabolism
Mice
Mice, Inbred Strains
Neuroprotective Agents--chemical synthesis
Protein Binding
Purinergic P1 Receptor Agonists
Rats
Rats, Inbred Strains