An isoenzyme-selective inhibitor of phosphodiesterase 4 and 1, KF19514, may be useful in the treatment of systemic anaphylaxis: an in vivo study in rabbits.

Hasome, N

An isoenzyme-selective inhibitor of phosphodiesterase 4 and 1, KF19514, may be useful in the treatment of systemic anaphylaxis: an in vivo study in rabbits. [electronic resource] - Shock (Augusta, Ga.) Jul 1999 - 46-53 p. digital

Publication Type: Journal Article

1073-2322

10.1097/00024382-199907000-00007 doi


3',5'-Cyclic-AMP Phosphodiesterases--antagonists & inhibitors
Anaphylaxis--drug therapy
Animals
Bronchodilator Agents--therapeutic use
Cyclic Nucleotide Phosphodiesterases, Type 4
Hemodynamics--drug effects
Isoenzymes--antagonists & inhibitors
Lung Compliance--drug effects
Naphthyridines--therapeutic use
Phosphodiesterase I
Phosphodiesterase Inhibitors--therapeutic use
Phosphoric Diester Hydrolases--metabolism
Rabbits