3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) induce hepatic expression of the phospholipid translocase mdr2 in rats.
Hooiveld, G J
3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) induce hepatic expression of the phospholipid translocase mdr2 in rats. [electronic resource] - Gastroenterology Sep 1999 - 678-87 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0016-5085
10.1016/s0016-5085(99)70462-2 doi
ATP Binding Cassette Transporter, Subfamily B--biosynthesis
ATP-Binding Cassette Transporters--biosynthesis
Animals
Anticholesteremic Agents--pharmacology
Bile--metabolism
Blotting, Western
Cholesterol--biosynthesis
Diosgenin--pharmacology
Hydroxymethylglutaryl-CoA Reductase Inhibitors--pharmacology
Immunohistochemistry
Liver--drug effects
Male
Phospholipids--biosynthesis
Pravastatin--pharmacology
RNA, Messenger--analysis
Rats
Rats, Wistar
Reverse Transcriptase Polymerase Chain Reaction
Simvastatin--pharmacology
ATP-Binding Cassette Sub-Family B Member 4
3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) induce hepatic expression of the phospholipid translocase mdr2 in rats. [electronic resource] - Gastroenterology Sep 1999 - 678-87 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0016-5085
10.1016/s0016-5085(99)70462-2 doi
ATP Binding Cassette Transporter, Subfamily B--biosynthesis
ATP-Binding Cassette Transporters--biosynthesis
Animals
Anticholesteremic Agents--pharmacology
Bile--metabolism
Blotting, Western
Cholesterol--biosynthesis
Diosgenin--pharmacology
Hydroxymethylglutaryl-CoA Reductase Inhibitors--pharmacology
Immunohistochemistry
Liver--drug effects
Male
Phospholipids--biosynthesis
Pravastatin--pharmacology
RNA, Messenger--analysis
Rats
Rats, Wistar
Reverse Transcriptase Polymerase Chain Reaction
Simvastatin--pharmacology
ATP-Binding Cassette Sub-Family B Member 4