Differential toxicities of TCDD in vivo among normal, c-src knockout, geldanamycin- and quercetin-treated mice.

Dunlap, D Y

Differential toxicities of TCDD in vivo among normal, c-src knockout, geldanamycin- and quercetin-treated mice. [electronic resource] - Toxicology Jul 1999 - 95-107 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

0300-483X

10.1016/s0300-483x(99)00054-2 doi


Adipose Tissue--growth & development
Analysis of Variance
Animals
Benzoquinones
Environmental Pollutants--toxicity
Enzyme Inhibitors--pharmacology
Lactams, Macrocyclic
Liver--growth & development
Male
Mice
Mice, Inbred C57BL
Mice, Inbred Strains
Mice, Knockout
Microsomes, Liver--drug effects
Organ Size--drug effects
Polychlorinated Dibenzodioxins--toxicity
Protein-Tyrosine Kinases--antagonists & inhibitors
Quercetin--pharmacology
Quinones--pharmacology
Radioligand Assay
Species Specificity
Thymus Gland--growth & development
Triglycerides--metabolism
Weight Gain--drug effects
src-Family Kinases--deficiency