Cocaine cytotoxicity in hepatocyte cultures from phenobarbital-induced rats: involvement of reactive oxygen species and expression of antioxidant defense systems.

Díez-Fernández, C

Cocaine cytotoxicity in hepatocyte cultures from phenobarbital-induced rats: involvement of reactive oxygen species and expression of antioxidant defense systems. [electronic resource] - Biochemical pharmacology Sep 1999 - 797-805 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0006-2952

10.1016/s0006-2952(99)00168-9 doi


Animals
Antioxidants--metabolism
Apoptosis
Catalase--genetics
Cells, Cultured
Cocaine--toxicity
Gene Expression Regulation, Enzymologic--drug effects
Liver--cytology
Male
Oxidative Stress
Phenobarbital--pharmacology
Rats
Rats, Wistar
Reactive Oxygen Species--metabolism
Superoxide Dismutase--genetics