Tumor-associated transforming growth factor-beta and interleukin-10 contribute to a systemic Th2 immune phenotype in pancreatic carcinoma patients.

Bellone, G

Tumor-associated transforming growth factor-beta and interleukin-10 contribute to a systemic Th2 immune phenotype in pancreatic carcinoma patients. [electronic resource] - The American journal of pathology Aug 1999 - 537-47 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0002-9440

10.1016/s0002-9440(10)65149-8 doi


Adenocarcinoma--immunology
Aged
Antibodies, Monoclonal
Culture Media, Conditioned--pharmacology
Dose-Response Relationship, Drug
Female
Humans
Immunophenotyping
Interferon-gamma--antagonists & inhibitors
Interleukin-10--biosynthesis
Interleukin-12--antagonists & inhibitors
Killer Cells, Lymphokine-Activated--immunology
Male
Middle Aged
Pancreatic Ducts--pathology
Pancreatic Neoplasms--immunology
Reverse Transcriptase Polymerase Chain Reaction
T-Lymphocytes--immunology
Th1 Cells--immunology
Th2 Cells--immunology
Transforming Growth Factor beta--biosynthesis
Tumor Cells, Cultured