An agouti mutation lacking the basic domain induces yellow pigmentation but not obesity in transgenic mice.
Miltenberger, R J
An agouti mutation lacking the basic domain induces yellow pigmentation but not obesity in transgenic mice. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Jul 1999 - 8579-84 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
0027-8424
10.1073/pnas.96.15.8579 doi
Agouti Signaling Protein
Animals
Body Weight
Gene Dosage
Gene Expression--genetics
Glycosylation
Intercellular Signaling Peptides and Proteins
Mice
Mice, Transgenic
Mutation
Obesity--genetics
Phenotype
Pigmentation--genetics
Promoter Regions, Genetic
Protein Sorting Signals--genetics
Proteins--genetics
RNA--analysis
Receptors, Corticotropin--antagonists & inhibitors
Receptors, Melanocortin
Sequence Deletion
Skin--metabolism
An agouti mutation lacking the basic domain induces yellow pigmentation but not obesity in transgenic mice. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Jul 1999 - 8579-84 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
0027-8424
10.1073/pnas.96.15.8579 doi
Agouti Signaling Protein
Animals
Body Weight
Gene Dosage
Gene Expression--genetics
Glycosylation
Intercellular Signaling Peptides and Proteins
Mice
Mice, Transgenic
Mutation
Obesity--genetics
Phenotype
Pigmentation--genetics
Promoter Regions, Genetic
Protein Sorting Signals--genetics
Proteins--genetics
RNA--analysis
Receptors, Corticotropin--antagonists & inhibitors
Receptors, Melanocortin
Sequence Deletion
Skin--metabolism