Phosphatidic acid is a potent and selective inhibitor of protein phosphatase 1 and an inhibitor of ceramide-mediated responses.

Kishikawa, K

Phosphatidic acid is a potent and selective inhibitor of protein phosphatase 1 and an inhibitor of ceramide-mediated responses. [electronic resource] - The Journal of biological chemistry Jul 1999 - 21335-41 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

0021-9258

10.1074/jbc.274.30.21335 doi


Animals
Ceramides--metabolism
Dose-Response Relationship, Drug
Enzyme Inhibitors--metabolism
Humans
Jurkat Cells
Phosphatidic Acids--metabolism
Phosphoprotein Phosphatases--antagonists & inhibitors
Protein Phosphatase 1
Protein Phosphatase 2
Rabbits
Retinoblastoma Protein--metabolism