A screening assay for antiviral compounds targeted to the HIV-1 gp41 core structure using a conformation-specific monoclonal antibody.

Jiang, S

A screening assay for antiviral compounds targeted to the HIV-1 gp41 core structure using a conformation-specific monoclonal antibody. [electronic resource] - Journal of virological methods Jun 1999 - 85-96 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0166-0934

10.1016/s0166-0934(99)00041-5 doi


Amino Acid Sequence
Anti-HIV Agents--metabolism
Antibodies, Monoclonal--metabolism
Cell Fusion
Enzyme-Linked Immunosorbent Assay--methods
HIV Antibodies--metabolism
HIV Envelope Protein gp41--chemistry
HIV-1--metabolism
Humans
Molecular Sequence Data
Peptides--metabolism
Point Mutation
Protein Conformation
Structure-Activity Relationship
Tumor Cells, Cultured