Mutations in the essential spindle checkpoint gene bub1 cause chromosome missegregation and fail to block apoptosis in Drosophila.

Basu, J

Mutations in the essential spindle checkpoint gene bub1 cause chromosome missegregation and fail to block apoptosis in Drosophila. [electronic resource] - The Journal of cell biology Jul 1999 - 13-28 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0021-9525

10.1083/jcb.146.1.13 doi


Animals
Apoptosis
Brain--cytology
Cell Cycle
Chromosome Segregation
Cloning, Molecular
Drosophila melanogaster--cytology
Epitopes--immunology
Genes, Essential--genetics
Genes, Insect--genetics
Kinetochores--immunology
Male
Meiosis
Mitosis
Molecular Sequence Data
Mutagenesis, Insertional
Mutation
Neurons--cytology
Phosphorylation
Protein Kinases--chemistry
Protein Serine-Threonine Kinases
Spermatogenesis
Spindle Apparatus--physiology