Nuclear DNA origin of mitochondrial complex I deficiency in fatal infantile lactic acidosis evidenced by transnuclear complementation of cultured fibroblasts.
Procaccio, V
Nuclear DNA origin of mitochondrial complex I deficiency in fatal infantile lactic acidosis evidenced by transnuclear complementation of cultured fibroblasts. [electronic resource] - The Journal of clinical investigation Jul 1999 - 83-92 p. digital
Publication Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't
0021-9738
10.1172/JCI6184 doi
Acidosis, Lactic--congenital
Cell Nucleus--chemistry
Cells, Cultured
DNA--genetics
DNA Mutational Analysis
DNA, Complementary--genetics
DNA, Mitochondrial--genetics
Electron Transport
Fatal Outcome
Fibroblasts--enzymology
Genetic Complementation Test
Genetic Heterogeneity
Humans
Hybrid Cells
Infant
Infant, Newborn
Male
Microscopy, Electron
NAD(P)H Dehydrogenase (Quinone)--deficiency
Organ Specificity
Transcription, Genetic
Nuclear DNA origin of mitochondrial complex I deficiency in fatal infantile lactic acidosis evidenced by transnuclear complementation of cultured fibroblasts. [electronic resource] - The Journal of clinical investigation Jul 1999 - 83-92 p. digital
Publication Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't
0021-9738
10.1172/JCI6184 doi
Acidosis, Lactic--congenital
Cell Nucleus--chemistry
Cells, Cultured
DNA--genetics
DNA Mutational Analysis
DNA, Complementary--genetics
DNA, Mitochondrial--genetics
Electron Transport
Fatal Outcome
Fibroblasts--enzymology
Genetic Complementation Test
Genetic Heterogeneity
Humans
Hybrid Cells
Infant
Infant, Newborn
Male
Microscopy, Electron
NAD(P)H Dehydrogenase (Quinone)--deficiency
Organ Specificity
Transcription, Genetic