Tyrosine phosphorylation of C-Cbl facilitates adhesion and spreading while suppressing anchorage-independent growth of V-Abl-transformed NIH3T3 fibroblasts.

Feshchenko, E A

Tyrosine phosphorylation of C-Cbl facilitates adhesion and spreading while suppressing anchorage-independent growth of V-Abl-transformed NIH3T3 fibroblasts. [electronic resource] - Oncogene Jun 1999 - 3703-15 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0950-9232

10.1038/sj.onc.1202672 doi


3T3 Cells
Actin Cytoskeleton--physiology
Actins--metabolism
Adaptor Proteins, Signal Transducing
Androstadienes--pharmacology
Animals
Carcinoma, Embryonal--pathology
Cell Adhesion--physiology
Cell Division
Cell Line, Transformed
Cell Size
Cell Transformation, Viral
Colony-Forming Units Assay
Cytoskeleton--physiology
Enzyme Inhibitors--pharmacology
Extracellular Matrix
Genes, abl
Kidney Neoplasms--pathology
Mice
Nuclear Proteins--physiology
Phosphatidylinositol 3-Kinases--physiology
Phosphoinositide-3 Kinase Inhibitors
Phosphorylation
Protein Processing, Post-Translational
Proto-Oncogene Proteins--chemistry
Proto-Oncogene Proteins c-cbl
Signal Transduction--physiology
Tumor Cells, Cultured
Ubiquitin-Protein Ligases
Wortmannin