Gene transfer of endothelial nitric oxide synthase to the lung of the mouse in vivo. Effect on agonist-induced and flow-mediated vascular responses.

Champion, H C

Gene transfer of endothelial nitric oxide synthase to the lung of the mouse in vivo. Effect on agonist-induced and flow-mediated vascular responses. [electronic resource] - Circulation research Jun 1999 - 1422-32 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0009-7330

10.1161/01.res.84.12.1422 doi


15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid--pharmacology
Adenoviridae
Angiotensin II--pharmacology
Animals
Antimetabolites, Antineoplastic
Bleomycin
Blood Flow Velocity--drug effects
Blood Pressure--drug effects
Bradykinin--pharmacology
Cyclic GMP--analysis
Endothelin-1--pharmacology
Gene Transfer Techniques
Genes, Reporter
Hypertension, Pulmonary--chemically induced
Hypoxia--metabolism
Mice
Mice, Inbred Strains
Nitric Oxide--metabolism
Nitric Oxide Synthase--genetics
Nitric Oxide Synthase Type II
Nitric Oxide Synthase Type III
Norepinephrine--pharmacology
Phosphodiesterase Inhibitors--pharmacology
Pulmonary Alveoli--blood supply
Pulmonary Artery--enzymology
Pulmonary Circulation--drug effects
Pulmonary Wedge Pressure--drug effects
Purinones--pharmacology
Sympathomimetics--pharmacology
Vasoconstrictor Agents--pharmacology
beta-Galactosidase--genetics