Blockade of nitric oxide formation down-regulates cyclooxygenase-2 and decreases PGE2 biosynthesis in macrophages.

Perkins, D J

Blockade of nitric oxide formation down-regulates cyclooxygenase-2 and decreases PGE2 biosynthesis in macrophages. [electronic resource] - Journal of leukocyte biology Jun 1999 - 792-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0741-5400

10.1002/jlb.65.6.792 doi


Animals
Cell Line
Cyclooxygenase 2
Dinoprostone--biosynthesis
Down-Regulation
Enzyme Inhibitors--pharmacology
Guanidines--pharmacology
Interferon-gamma--pharmacology
Isoenzymes--biosynthesis
Macrophages--cytology
Nitric Oxide--metabolism
Nitric Oxide Synthase--physiology
Nitric Oxide Synthase Type II
Peroxidases--physiology
Prostaglandin-Endoperoxide Synthases--biosynthesis