Influence of sulphasalazine, methotrexate, and the combination of both on plasma homocysteine concentrations in patients with rheumatoid arthritis.

Haagsma, C J

Influence of sulphasalazine, methotrexate, and the combination of both on plasma homocysteine concentrations in patients with rheumatoid arthritis. [electronic resource] - Annals of the rheumatic diseases Feb 1999 - 79-84 p. digital

Publication Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

0003-4967

10.1136/ard.58.2.79 doi


Antirheumatic Agents--adverse effects
Arthritis, Rheumatoid--blood
Digestive System--drug effects
Double-Blind Method
Drug Therapy, Combination
Female
Folic Acid--blood
Homocysteine--blood
Humans
Male
Methotrexate--adverse effects
Methylenetetrahydrofolate Reductase (NADPH2)
Middle Aged
Mutation
Oxidoreductases Acting on CH-NH Group Donors--genetics
Sulfasalazine--adverse effects
Vitamin B 12--blood