Presenilin 1 facilitates the constitutive turnover of beta-catenin: differential activity of Alzheimer's disease-linked PS1 mutants in the beta-catenin-signaling pathway.

Kang, D E

Presenilin 1 facilitates the constitutive turnover of beta-catenin: differential activity of Alzheimer's disease-linked PS1 mutants in the beta-catenin-signaling pathway. [electronic resource] - The Journal of neuroscience : the official journal of the Society for Neuroscience Jun 1999 - 4229-37 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

1529-2401


Adenomatous Polyposis Coli--metabolism
Alzheimer Disease--genetics
Animals
Brain--metabolism
Cadherins--physiology
Calcium-Calmodulin-Dependent Protein Kinases--metabolism
Cell Line
Cytoskeletal Proteins--metabolism
Glycogen Synthase Kinase 3
Glycogen Synthase Kinases
Membrane Proteins--genetics
Mice
Mice, Transgenic
Mutation
Presenilin-1
Signal Transduction--physiology
Trans-Activators
beta Catenin