Characterization of antiallodynic actions of ALE-0540, a novel nerve growth factor receptor antagonist, in the rat.

Owolabi, J B

Characterization of antiallodynic actions of ALE-0540, a novel nerve growth factor receptor antagonist, in the rat. [electronic resource] - The Journal of pharmacology and experimental therapeutics Jun 1999 - 1271-6 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0022-3565


Analgesics--administration & dosage
Animals
Cells, Cultured
Chick Embryo
Dose-Response Relationship, Drug
Ganglia, Spinal--cytology
Heterocyclic Compounds, 3-Ring--administration & dosage
Hot Temperature
Inflammation
Injections, Intraperitoneal
Injections, Spinal
Mice
Morphine--pharmacology
Nerve Growth Factors--metabolism
Neuralgia--physiopathology
Neurites--drug effects
Neurons, Afferent--drug effects
Pain--physiopathology
Phosphorylation
Proto-Oncogene Proteins--antagonists & inhibitors
Radioligand Assay
Rats
Receptor Protein-Tyrosine Kinases--antagonists & inhibitors
Receptor, trkA
Receptors, Nerve Growth Factor--antagonists & inhibitors
Spinal Cord--drug effects
Spinal Nerves--drug effects