Overexpression of wild-type and catalytically inactive forms of GRK2 and GRK6 fails to alter the agonist-induced phosphorylation of the C5a receptor (CD88): evidence that GRK6 is autophosphorylated in COS-7 cells.

Milcent, M D

Overexpression of wild-type and catalytically inactive forms of GRK2 and GRK6 fails to alter the agonist-induced phosphorylation of the C5a receptor (CD88): evidence that GRK6 is autophosphorylated in COS-7 cells. [electronic resource] - Biochemical and biophysical research communications May 1999 - 224-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0006-291X

10.1006/bbrc.1999.0758 doi


Amino Acid Sequence
Animals
Antigens, CD--metabolism
COS Cells
Complement C5a--genetics
Cyclic AMP-Dependent Protein Kinases--genetics
Enzyme Inhibitors--pharmacology
G-Protein-Coupled Receptor Kinases
Gene Expression--genetics
Humans
Kinetics
Molecular Sequence Data
Mutagenesis, Site-Directed
Mutation--genetics
Okadaic Acid--pharmacology
Phosphorylation
Protein Serine-Threonine Kinases
Receptor Protein-Tyrosine Kinases--genetics
Receptor, Anaphylatoxin C5a
Receptors, Complement--metabolism
Recombinant Proteins--metabolism
Transfection
beta-Adrenergic Receptor Kinases