Bone morphogenetic protein-2 enhances osteoclast formation mediated by interleukin-1alpha through upregulation of osteoclast differentiation factor and cyclooxygenase-2.

Koide, M

Bone morphogenetic protein-2 enhances osteoclast formation mediated by interleukin-1alpha through upregulation of osteoclast differentiation factor and cyclooxygenase-2. [electronic resource] - Biochemical and biophysical research communications May 1999 - 97-102 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0006-291X

10.1006/bbrc.1999.0715 doi


Activins
Animals
Bone Development--drug effects
Bone Marrow Cells
Bone Morphogenetic Protein 2
Bone Morphogenetic Proteins--pharmacology
Carrier Proteins--metabolism
Cyclooxygenase 2
Cyclooxygenase 2 Inhibitors
Cyclooxygenase Inhibitors--pharmacology
Gene Expression Regulation, Developmental
Indomethacin--pharmacology
Inhibins--pharmacology
Interleukin-1--pharmacology
Isoenzymes--metabolism
Membrane Glycoproteins--metabolism
Mice
Mice, Inbred Strains
Nitrobenzenes--pharmacology
Osteoclasts--physiology
Prostaglandin-Endoperoxide Synthases--metabolism
RANK Ligand
RNA, Messenger--metabolism
Receptor Activator of Nuclear Factor-kappa B
Sulfonamides--pharmacology
Transforming Growth Factor beta--pharmacology
Up-Regulation--genetics