Exogenous hyperinsulinemia causes insulin resistance, hyperendothelinemia, and subsequent hypertension in rats.

Juan, C C

Exogenous hyperinsulinemia causes insulin resistance, hyperendothelinemia, and subsequent hypertension in rats. [electronic resource] - Metabolism: clinical and experimental Apr 1999 - 465-71 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0026-0495

10.1016/s0026-0495(99)90105-1 doi


Adipocytes--drug effects
Animals
Blood Glucose--metabolism
Blood Pressure--drug effects
Cell Membrane--metabolism
Endothelin-1--metabolism
Endothelium, Vascular--drug effects
Glucose Tolerance Test
Hyperinsulinism--blood
Hypertension--chemically induced
Hypoglycemic Agents--blood
Insulin--blood
Insulin Infusion Systems
Insulin Resistance--physiology
Male
Rats
Rats, Sprague-Dawley