Fialuridine and its metabolites inhibit DNA polymerase gamma at sites of multiple adjacent analog incorporation, decrease mtDNA abundance, and cause mitochondrial structural defects in cultured hepatoblasts.
Fialuridine and its metabolites inhibit DNA polymerase gamma at sites of multiple adjacent analog incorporation, decrease mtDNA abundance, and cause mitochondrial structural defects in cultured hepatoblasts. — المؤلف: Lewis, W — Proceedings of the National Academy of Sciences of the United States of America 19960618
- المؤلف
- Lewis, W
- النشر
- Proceedings of the National Academy of Sciences of the United States of America 19960618
- الوصف
- 3592-7 p.
- الموضوعات
- Antiviral Agents؛ Arabinofuranosyluracil؛ Base Sequence؛ Binding Sites؛ Cell Line؛ DNA Polymerase III؛ DNA Primers؛ DNA, Mitochondrial