Kinetic Profile and Molecular Dynamic Studies Show that Y229W Substitution in an NDM-1/L209F Variant Restores the Hydrolytic Activity of the Enzyme toward Penicillins, Cephalosporins, and Carbapenems.

Kinetic Profile and Molecular Dynamic Studies Show that Y229W Substitution in an NDM-1/L209F Variant Restores the Hydrolytic Activity of the Enzyme toward Penicillins, Cephalosporins, and Carbapenems. — المؤلف: Piccirilli, Alessandra — Antimicrobial agents and chemotherapy 20200226

المؤلف
Piccirilli, Alessandra
النشر
Antimicrobial agents and chemotherapy 20200226
الموضوعات
Amino Acid Substitution؛ Anti-Bacterial Agents؛ Carbapenems؛ Catalytic Domain؛ Cephalosporins؛ Hydrolysis؛ Kinetics؛ Microbial Sensitivity Tests