Discovery of Polypharmacological Melanocortin-3 and -4 Receptor Probes and Identification of a 100-Fold Selective nM MC3R Agonist versus a μM MC4R Partial Agonist.

Name: Discovery of Polypharmacological Melanocortin-3 and -4 Receptor Probes and Identification of a 100-Fold Selective nM MC3R Agonist versus a μM MC4R Partial Agonist.
Author: Fleming, Katlyn A

Discovery of Polypharmacological Melanocortin-3 and -4 Receptor Probes and Identification of a 100-Fold Selective nM MC3R Agonist versus a μM MC4R Partial Agonist. — المؤلف: Fleming, Katlyn A — Journal of medicinal chemistry 20200406

المؤلف: Fleming, Katlyn A
النشر: Journal of medicinal chemistry 20200406
الوصف: 2738-2749 p.
الموضوعات: Animals؛ Drug Discovery؛ Mice؛ Molecular Probes؛ Polypharmacology؛ Receptor, Melanocortin, Type 3؛ Receptor, Melanocortin, Type 4؛ Structure-Activity Relationship