RAF inhibitor PLX8394 selectively disrupts BRAF dimers and RAS-independent BRAF-mutant-driven signaling.
RAF inhibitor PLX8394 selectively disrupts BRAF dimers and RAS-independent BRAF-mutant-driven signaling. — المؤلف: Yao, Zhan — Nature medicine 20190510
- المؤلف
- Yao, Zhan
- النشر
- Nature medicine 20190510
- الوصف
- 284-291 p.
- الموضوعات
- Cell Line, Tumor؛ Cell Proliferation؛ Extracellular Signal-Regulated MAP Kinases؛ Heterocyclic Compounds, 2-Ring؛ Humans؛ Mutation؛ Phosphorylation؛ Protein Multimerization