Synthesis and pharmacological characterization of O-alkynyloximes of tropinone and N-methylpiperidinone as muscarinic agonists. [electronic resource]
Producer: 19980909Description: 3220-31 p. digitalISSN:- 0022-2623
- Animals
- Aorta -- drug effects
- Binding, Competitive
- Drug Design
- Escape Reaction -- drug effects
- In Vitro Techniques
- Male
- Maze Learning -- drug effects
- Mice
- Models, Molecular
- Molecular Structure
- Muscarinic Agonists -- chemical synthesis
- Muscle Contraction -- drug effects
- Muscle, Smooth, Vascular -- drug effects
- N-Methylscopolamine -- pharmacology
- Nuclear Magnetic Resonance, Biomolecular
- Piperidines -- chemical synthesis
- Pirenzepine -- metabolism
- Rabbits
- Rats
- Rats, Sprague-Dawley
- Receptors, Muscarinic -- drug effects
- Structure-Activity Relationship
- Tropanes -- chemical synthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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