Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides activate monocytic cells via a CD14-dependent pathway distinct from that used by lipopolysaccharide. [electronic resource]
Producer: 19980611Description: 5455-64 p. digitalISSN:- 0022-1767
- Acute-Phase Proteins
- Animals
- Antibodies, Blocking -- pharmacology
- Bacterial Proteins -- pharmacology
- Borrelia burgdorferi Group -- immunology
- Carrier Proteins -- blood
- Cell Differentiation -- drug effects
- Cell Line
- Cholecalciferol -- pharmacology
- Female
- Humans
- Immune Sera -- pharmacology
- Immunosuppressive Agents -- pharmacology
- Interleukin-8 -- metabolism
- Lipopolysaccharide Receptors -- biosynthesis
- Lipopolysaccharides -- blood
- Lipoproteins -- blood
- Macrophage Activation -- drug effects
- Membrane Glycoproteins
- Membrane Proteins -- immunology
- Mice
- Mice, Inbred BALB C
- Mice, Knockout
- Monocytes -- immunology
- Peptides -- chemical synthesis
- Signal Transduction -- immunology
- Treponema pallidum -- immunology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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