CTLA-4 ligation delivers a unique signal to resting human CD4 T cells that inhibits interleukin-2 secretion but allows Bcl-X(L) induction. [electronic resource]
Producer: 19980507Description: 12-5 p. digitalISSN:- 0022-1767
- Abatacept
- Antibodies, Monoclonal
- Antigens, CD
- Antigens, Differentiation -- physiology
- CD4-Positive T-Lymphocytes -- physiology
- CTLA-4 Antigen
- Cell Cycle
- Cells, Cultured
- Gene Expression
- Humans
- Immunoconjugates
- Interleukin-2 -- metabolism
- Lymphocyte Activation
- Proto-Oncogene Proteins c-bcl-2 -- physiology
- RNA, Messenger -- genetics
- Signal Transduction
- bcl-X Protein
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
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