Hepatic foci in rats after diethylnitrosamine initiation and 2,3,7,8-tetrachlorodibenzo-p-dioxin promotion: evaluation of a quantitative two-cell model and of CYP 1A1/1A2 as a dosimeter. [electronic resource]
Producer: 19971124Description: 281-93 p. digitalISSN:- 0041-008X
- Animals
- Apoptosis -- drug effects
- Carcinogens -- toxicity
- Computer Simulation
- Cytochrome P-450 CYP1A1 -- analysis
- Cytochrome P-450 CYP1A2 -- analysis
- Diethylnitrosamine -- toxicity
- Dose-Response Relationship, Drug
- Female
- Gene Expression Regulation, Enzymologic -- drug effects
- Liver -- drug effects
- Liver Neoplasms, Experimental -- chemically induced
- Models, Biological
- Mutation -- drug effects
- Polychlorinated Dibenzodioxins -- toxicity
- Rats
- Retrospective Studies
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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