Aldosterone blockade reduces vascular collagen turnover, improves heart rate variability and reduces early morning rise in heart rate in heart failure patients. [electronic resource]
Producer: 19971016Description: 30-4 p. digitalISSN:- 0008-6363
- Aged
- Angiotensin-Converting Enzyme Inhibitors -- therapeutic use
- Biomarkers -- blood
- Circadian Rhythm
- Diuretics -- therapeutic use
- Double-Blind Method
- Drug Therapy, Combination
- Electrocardiography, Ambulatory
- Female
- Fibrosis
- Heart Failure -- blood
- Heart Rate -- drug effects
- Humans
- Male
- Mineralocorticoid Receptor Antagonists -- therapeutic use
- Myocardium -- pathology
- Peptide Fragments -- blood
- Procollagen -- blood
- Spironolactone -- therapeutic use
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Publication Type: Clinical Trial; Journal Article; Randomized Controlled Trial
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