5alpha-reduction of norethisterone enhances its binding affinity for androgen receptors but diminishes its androgenic potency. [electronic resource]
Producer: 19970710Description: 121-9 p. digitalISSN:- 0960-0760
- Androgens -- physiology
- Animals
- Binding, Competitive
- Dose-Response Relationship, Drug
- Drug Synergism
- Ethisterone -- metabolism
- Glucuronidase -- drug effects
- Kidney -- drug effects
- Male
- Mice
- Mice, Inbred BALB C
- Nandrolone -- analogs & derivatives
- Norethindrone -- analogs & derivatives
- Orchiectomy
- Organ Size -- drug effects
- Oxidation-Reduction
- Progesterone Congeners -- metabolism
- Prostate -- drug effects
- Rats
- Rats, Wistar
- Receptors, Androgen -- metabolism
- Seminal Vesicles -- drug effects
- Structure-Activity Relationship
- Testosterone -- analogs & derivatives
- Tritium
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Publication Type: Comparative Study; Journal Article
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