A molecular basis for affinity modulation of Fab ligand binding to integrin alphaIIb beta3. [electronic resource]
Producer: 19961011Description: 20315-21 p. digitalISSN:- 0021-9258
- Amino Acid Sequence
- Animals
- Antigens, CD -- metabolism
- Base Sequence
- Blood Platelets -- metabolism
- CHO Cells
- Cations, Divalent
- Cricetinae
- DNA Primers -- chemistry
- Humans
- Immunoglobulin Fab Fragments -- chemistry
- Integrin alpha2
- Integrin alpha5
- Integrin beta3
- Ligands
- Molecular Sequence Data
- Oligopeptides
- Platelet Activation
- Platelet Glycoprotein GPIIb-IIIa Complex -- metabolism
- Platelet Membrane Glycoproteins -- metabolism
- Protein Conformation
- Recombinant Proteins
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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