Inhibition of human immunodeficiency virus type 1 integrase by the Fab fragment of a specific monoclonal antibody suggests that different multimerization states are required for different enzymatic functions. [electronic resource]
Producer: 19960815Description: 4484-94 p. digitalISSN:- 0022-538X
- Antibodies, Monoclonal -- genetics
- Base Sequence
- Cloning, Molecular
- DNA Nucleotidyltransferases -- antagonists & inhibitors
- DNA, Viral -- metabolism
- Epitope Mapping
- HIV Antibodies -- genetics
- HIV-1 -- enzymology
- Humans
- Immunoglobulin Fab Fragments -- genetics
- Integrases
- Molecular Sequence Data
- Protein Binding
- Structure-Activity Relationship
- Virus Integration
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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