Identification, characterization and pharmacological profile of three metabolites of (R)-(+)-1,2,3,6-tetrahydro-4-phenyl-1-[(3-phenylcyclohexen-1- yl)methyl]pyridine (CI-1007), a dopamine autoreceptor agonist and potential antipsychotic agent. [electronic resource]
Producer: 19960213Description: 5007-14 p. digitalISSN:- 0022-2623
- 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine -- analogs & derivatives
- Animals
- Antipsychotic Agents -- chemical synthesis
- Autoreceptors -- metabolism
- Avoidance Learning -- drug effects
- Brain -- metabolism
- CHO Cells
- Chromatography, High Pressure Liquid
- Cricetinae
- Dopamine -- metabolism
- Dopamine Agonists -- chemical synthesis
- Humans
- Hydroxylation
- Magnetic Resonance Spectroscopy
- Mass Spectrometry
- Mice
- Motor Activity -- drug effects
- Rats
- Receptors, Dopamine -- metabolism
- Saimiri
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Publication Type: Journal Article
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