Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation. [electronic resource]
Producer: 19940624Description: 3938-48 p. digitalISSN:- 0270-7306
- Adenovirus E2 Proteins -- biosynthesis
- Amino Acid Sequence
- Base Sequence
- Binding Sites
- Chromosomes, Human, Pair 1
- Chromosomes, Human, Pair 19
- Consensus Sequence
- DNA -- metabolism
- DNA Primers
- DNA-Binding Proteins -- biosynthesis
- Gene Rearrangement
- Genes, Homeobox
- Glutathione Transferase -- biosynthesis
- Humans
- Molecular Sequence Data
- Multigene Family
- Oligodeoxyribonucleotides
- Point Mutation
- Polymerase Chain Reaction
- Pre-B-Cell Leukemia Transcription Factor 1
- Precursor B-Cell Lymphoblastic Leukemia-Lymphoma -- genetics
- Proto-Oncogene Proteins -- biosynthesis
- Recombinant Fusion Proteins -- biosynthesis
- Transcription, Genetic
- Translocation, Genetic
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
There are no comments on this title.
Log in to your account to post a comment.