Adenovirus-mediated transfer of a gene encoding cholesterol 7 alpha-hydroxylase into hamsters increases hepatic enzyme activity and reduces plasma total and low density lipoprotein cholesterol. [electronic resource]
Producer: 19950911Description: 700-9 p. digitalISSN:- 0021-9738
- Adenoviridae -- genetics
- Animals
- Bile Acids and Salts -- metabolism
- Cholesterol -- blood
- Cholesterol 7-alpha-Hydroxylase -- genetics
- Cholesterol, LDL -- blood
- Cholestyramine Resin -- metabolism
- Cricetinae
- DNA, Complementary -- genetics
- Diet, Atherogenic
- Enzyme Induction
- Genetic Vectors
- Male
- Mesocricetus
- Microsomes, Liver -- enzymology
- Rats
- Recombinant Fusion Proteins -- metabolism
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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