Dose requirements, assay procedures and tissue specificity for PCB inductation of P-450 dependent mono-oxygenase activity in the rat: implications for design of studies measuring in vivo induction of human placental mono-oxygenases. [electronic resource]
Producer: 19871007Description: 81-90 p. digitalISSN:- 0260-437X
- Animals
- Aryl Hydrocarbon Hydroxylases -- biosynthesis
- Cytochrome P-450 Enzyme System -- biosynthesis
- Enzyme Induction -- drug effects
- Female
- Fetus -- metabolism
- Kinetics
- Liver -- enzymology
- Microsomes -- enzymology
- Microsomes, Liver -- enzymology
- Mixed Function Oxygenases -- antagonists & inhibitors
- Organ Size -- drug effects
- Placenta -- enzymology
- Polychlorinated Biphenyls -- metabolism
- Pregnancy
- Rats
- Rats, Inbred F344
- Rats, Inbred Strains
- Reproduction -- drug effects
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Publication Type: Journal Article
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